We rank the 10 Best Spring Break Destinations. to be spring break -worthy, it's got to be affordable, accessible and popular among the college cohort. The best spring break of your life! All-inclusive spring break packages to hot destinations with the best nightlife, wild activities, and crazy fun. The City of Stars, and other hotspots, await your arrival. Pick one of the 10 best college spring break destinations for the trip of a lifetime. It is a less expensive alternative to Miami, Florida's other uber-popular spring break spot more on that later. Negril Tree House has a prime location in the heart of the action -- right on Seven Mile Beach and next door to great bars and restaurants. This list of fun ideas and travel destinations will guarantee the best college spring break yet! More From Travel Sweepstakes Travel's Best Newsletters Stream Travel Channel Get Travel Channel: South Padre Island is among the TOP Spring Break destinations in the USA. LIFESTYLE Healthy Living Travel Style Taste Home Relationships Horoscopes. Chic clubs with discerning bouncers draw the fashion-industry elite, the occasional celebrity, and plenty of somethings ready to party. The Bahamas are just as beautiful, as clear-watered and as exciting as any travel brochure sells them off to be. Rent a jet ski and jet the day away or go scuba diving and see the life merkus casino there up close. Negril Tree House Resort. Add in crazy cheap off-property hotels and this is one of the more underrated Spring Break destinations in America. Cancun Despite its "Man-cun" reputation, the dude-heavy originator of all-you-can-drink SB debauchery is still going strong. Shows Main Program Guide Full Episodes Watch Live All Shows Hotel Impossible Bizarre Foods: By Traveler Family Travel Girls' Getaways Guy Trips LGBT Travel Solo Travel. Fifteen-hour days full of dashing from class-to-class, meetings When we first thought about visiting Key West, FL we pictured a big old college spring break and thought we would have to cover our kids eyes the whole time we were there!